https://doi.org/10.1038/s41586-024-08501-x
A strain of E. coli was recoded to utilize only the UAA stop codon. Called "Ochre," this strain will be utilized in biotechnological and biotherapeutic applications for the incorporation of noncanonical amino acids in synthetic protein constructs.
https://doi.org/10.1021/acsami.9b05401
Synthetic DNA strands were constructed to build vesicular tubes from modifying the lipid bilayer into a cylindrical structure. DNA nanotechnology could then be used in membrane deformation and scission machines to transport ligands between membranes.
https://doi.org/10.1126/science.abh3571
A number of bacteriophages have been found to have replaced their Adenine nucleotide with a Z-nucleotide, forming a triple hydrogen bond with Thymine. Recent interest in Z-genomes could result in novel materials and biotechnology.
https://doi.org/10.1038/nature14095
Genomically recoded organisms exhibit potential in biocontainment strategies of modified organisms. A strain of E. coli lacking all TAG codons was engineered to depend on synthetic amino acids for the synthesis of essential genes through the conversion of the TAG codon to a sense codon.